Can C, Baseskioglu B, Yılmaz M, Colak E, Ozen A, Yenilmez A. Platelets and granulocytes, in particular the neutrophils, form important compartments for circulating vascular endothelial growth factor. Kusumanto YH, Dam WA, Hospers GA, Meijer C, Mulder NH. Inflammation and cancer: causes and consequences. Platelets at the interface of thrombosis, inflammation, and cancer. Platelets: bridging hemostasis, inflammation, and immunity. White blood cell counts and neutrophil to lymphocyte ratio in the diagnosis of testicular cancer: a simple secondary serum tumor marker. Yuksel OH, Verit A, Sahin A, Urkmez A, Uruc F. Maintaining success, reducing treatment burden, focusing on survivorship: highlights from the third European consensus conference on diagnosis and treatment of germ-cell cancer. Beyer J, Albers P, Altena R, Aparicio J, Bokemeyer C, Busch J, et al. Metachronous Testicular Cancer After Orchiectomy: A Rare Case. Is platelet mass a more significant indicator than platelet count of closure of patent ductus arteriosus? J Matern Fetal Neonatal Med. Demir N, Peker E, Ece İ, Ağengin K, Bulan KA, Tuncer O. Platelet microparticles and cancer: An intimate cross-talk. Goubran H, Sabry W, Kotb R, Seghatchian J, Burnouf T. Goubran HA, Stakiw J, Radosevic M, Burnouf T. Activated Platelets Induce an Anti-Inflammatory Response of Monocytes/Macrophages through Cross-Regulation of PGE2 and Cytokines. Linke B, Schreiber Y, Picard-Willems B, Slattery P, Nüsing RM, Harder S, et al. Updates and Critical Evaluation on Novel Biomarkers for the Malignant Progression of Intraductal Papillary Mucinous Neoplasms of the Pancreas. Moris D, Damaskos C, Spartalis E, Papalampros A, Vernadakis S, Dimitroulis D, et al. Preoperative independent prognostic factors in patients with borderline resectable pancreatic ductal adenocarcinoma following curative resection: the neutrophil-lymphocyte and platelet-lymphocyte ratios. Asari S, Matsumoto I, Toyama H, Shinzeki M, Goto T, Ishida J, et al. Promoting effect of neutrophils on lung tumorigenesis is mediated by CXCR2 and neutrophil elastase. Gong L, Cumpian AM, Caetano MS, Ochoa CE, De la Garza MM, Lapid DJ, et al. Inflammation and cancer: back to Virchow? Lancet. Resultados: El número de plaquetas y los valores de PMI fueron estadísticamente significativamente más altos en los pacientes con cáncer testicular en comparación con el grupo de control (p <.05).Ĭonclusiones: Tanto el recuento de plaquetas como los valores de PMI se pueden utilizar como una prueba simple en el diagnóstico de cáncer testicular, además de los marcadores tumorales séricos precisos bien conocidos como AFP (alfa fetoproteína), hCG (gonadotropina coriónica humana) y LDH (lactato deshidrogenasa). El número de plaquetas, el volumen medio de plaquetas y el valor de PMI se calcularon a partir de muestras de sangre periférica obtenidas. Materiales y métodos: Se incluyeron en el estudio 38 pacientes con cáncer testicular localizado con una edad media de 30,84 ± 5,79 años y 38 pacientes con varicocele como grupo control con una edad media de 32,8 ± 9,7 años. En este contexto, nos centramos en los efectos del recuento de plaquetas y el índice de masa plaquetaria (PMI) como marcadores inflamatorios en el diagnóstico de cáncer testicular localizado de bajo volumen. Hay muchos marcadores inflamatorios estudiados con este propósito en la literatura. Introducción: La relación entre la inflamación y el cáncer ha sido durante mucho tiempo el foco de interés de los investigadores. Results: Number of platelets and PMI values were statistically significantly higher in patients with testicular cancer compared with the control group (p<.05).Ĭonclusions: Both platelet counts and PMI values can be used as a simple test in the diagnosis of testicular cancer besides the well-known accurate serum tumor markers as AFP (alpha fetoprotein), hCG (human chorionic gonadotropin) and LDH (lactate dehydrogenase). Number of platelets, mean platelet volume and value of PMI were calculated from peripheral blood samples obtained. Materials and methods: Thirty-eight patients with localized testicular cancer with a mean age of 30.84 ± 5.79 years and 38 patients with varicocele as a control group with a mean age of 32.8 ± 9.7 years were enrolled in the study. In this context, we focused on the effects of platelet counts and platelet mass index (PMI) as inflammatory markers in the diagnosis of low-volume localized testicular cancer. There are many inflammatory markers studied for this purpose in the literature. Introduction: The relationship between inflammation and cancer has long been the focus of researchers' interest.
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